Because of increased Bacterial resistance and many side effects of Allopathic drugs, it has become necessary today to use traditional medicine in medical problems. In the past decade, much research has been directed on therapeutic evaluation of traditional drugs of plant origin. Momordica Charantia is a medicinal plant that has been used as medicine. The present study review the Research work done on plant Momordica charantia, with respect to its various Chemical contents, Therapeutic acitivites, uses and Medicinal details.