Review Article
Open Access
Advances in Precision Medicine and Targeted Pharmacotherapy: A Comprehensive Review of Emerging Technologies, Clinical Applications, and Future Challenges
Bárbara Andrews, Joana Fonseca*
Professor, Environmental Health Department of the School of Health of the Polytechnic Institute of Porto, Portugal
Joana Fonseca, et al. Advances in Precision Medicine and Targeted Pharmacotherapy: A Comprehensive Review of Emerging Technologies, Clinical Applications, and Future Challenges.Int.J. MediPharm Res. 2022,8(1),pp 1-16
Abstract
Precision medicine has rapidly evolved from a theoretical concept to a cornerstone of modern clinical and pharmaceutical sciences. The integration of multi-omics technologies, artificial intelligence (AI), biomarker-guided drug development, and innovative therapeutic modalities such as gene editing and mRNA platforms has ushered in a new era of individualized care. This review synthesizes recent advances in medical and pharmaceutical precision technologies, evaluates their translational and clinical applications, and examines ongoing limitations related to data integration, regulatory frameworks, and equity in access. We conclude with a forward-looking perspective on how next-generation computational modeling, real-time biological monitoring, and personalized drug manufacturing may redefine the therapeutic landscape.
Keywords
Core Concepts & Fields, Precision medicine, Individualized care, Paradigm shift, One-size-fitsall medicine, Genomics, Proteomics, Pharmacogenomics, Bioinformatics, Regulatory science, Technologies & Methods, High-throughput sequencing, AI-enabled drug discovery, Predictive biomarkers, Clinical translation, Implementation barriers, Therapeutics & Applications, Disease prevention, Treatment strategies, Drug selection, Adverse drug reactions (ADRs), Pharmaceutical innovation, Targeted small molecules, Therapeutic antibodies, Adoptive cell therapies, RNA therapeutics, CRISPR-based interventions
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